Symptoms of acute stroke | Time is Brain

Stroke symptoms include:

  • SUDDEN numbness or weakness of face, arm or leg – especially on one side of the body.
  • SUDDEN confusion, trouble speaking or understanding.
  • SUDDEN trouble seeing in one or both eyes.
  • SUDDEN trouble walking, dizziness, loss of balance or coordination.
  • SUDDEN severe headache with no known cause. Call 9-1-1 immediately if you have any of these symptoms

Flawed studies

Source AAN:  http://journals.lww.com/neurotodayonline/Fulltext/2016/03030/Phenytoin_Appears_Neuroprotective_of_Retinal_Nerve.6.aspx

IMO:

I am sure PHT has far more adverse effects on nervous system than just some questionable neuroprotective effect on retinal nerve. I would urge NIH to stop funding these type of studies which fail to add any meaningful benefit to society. Just a waste of time and money of society. Of course author will add one more publication to their list, which seems to be goal now a days for those working at academic centers.

Not sure why we even worry about studying one variable at a time anymore. Biological organisms are complex and there is interaction between multiple variables at every moment of time. This is the reason why one study says something and another study on same the variable says something exactly opposite. They failed to look at the interaction the between major variables and hence came to different conclusion. example: coffee consumption. We got to change the way we do research studies.

Effect of brain on heart : sudden unexpected death in epilepsy (SUDEP)

Source:
http://www.neurologytimes.com/epilepsy-and-seizure/cardiac-findings-highlight-epilepsy-conference

Abnormalities in cardiac repolarization may dangerously slow the heart rate and induce asystole during the post-seizure state and significantly raise the risk of sudden unexpected death in epilepsy (SUDEP), researchers at the University of Florida College of Medicine found.

Their findings and others that describe the link between cardiac abnormalities and SUDEP were presented at the American Epilepsy Society’s (AES) 68th Annual Meeting held December 5-9 in Seattle.

Stroke : Cognitive Impairment Increase Stroke Risk?

Source: http://journals.lww.com/neurotodayonline/blog/breakingnews/pages/post.aspx?PostID=359

“Participants who were cognitively impaired at baseline had a 39 percent higher risk of stroke than those with normal cognitive function, the researchers found. Cognitive impairment was associated with a high risk of ischemic and fatal stroke in particular.

Stroke risk increased to 64 percent when the authors broadened the definition of cognitive impairment.

Cognitive impairment should be more broadly recognized as a possible early clinical manifestation of cerebral infarction, so that timely management of vascular risk factors can be instituted to potentially prevent future stroke events and to avoid further deterioration of cognitive health,………”

Source: http://journals.lww.com/neurotodayonline/blog/breakingnews/pages/post.aspx?PostID=359

“Oral fluoroquinolone use and risk of peripheral neuropathy” Source Neurology.org

Saw a  similar case recently.

http://www.neurology.org/content/early/2014/08/22/WNL.0000000000000846.short?rss=1

 

“Conclusions: Current users, especially new users of FQs, are at a higher risk of developing PN. Despite the increase in the use of FQs, clinicians should weigh the benefits against the risk of adverse events when prescribing these drugs to their patients.”